JPET Celsis microsomes equal better data

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Oberst, F. W.
Right arrow Articles by Snyder, F. H.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Oberst, F. W.
Right arrow Articles by Snyder, F. H.
Journal of Pharmacology And Experimental Therapeutics, Vol. 93, Issue 3, 444-450, 1948
Copyright © 1948 by American Society for Pharmacology and Experimental Therapeutics

STUDIES ON NITRATE ESTERS

I. NITRITE-PRODUCING SYSTEMS IN RABBIT TISSUES

Fred W. Oberst 1 and Fred H. Snyder 2

1 The Murray Foundation, Inc., Cincinnati 29, Ohio
2 Research Laboratories, The Wm. S. Merrell Co., Cincinnati, Ohio

Inorganic nitrite is formed from nitrate esters of polyhydric alcohols by two systems occurring in normal rabbit tissues. The first, occurring principally in the liver, is heat-labile. The second, found in liver, muscle, and blood, is activated or released from combination by heat. The system as present in fresh liver homogenate shows maximal activity in the neighborhood of pH 8.4; after acidification to pH 2, it regains most of its activity on re-neutralization.

Submitted on April 16, 1948






Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1948 by the American Society for Pharmacology and Experimental Therapeutics.