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Journal of Pharmacology And Experimental Therapeutics, Vol. 93, Issue 3, 430-433, 1948
Copyright © 1948 by American Society for Pharmacology and Experimental Therapeutics

CHEMOTHERAPEUTIC STUDIES ON A SERIES OF DITHIOCARBAMATES AND THEIR BISMUTH DERIVATIVES

Andres Goth 1 and Fabian J. Robinson 1

1 Department of Physiology and Pharmacology, Southwestern Medical College, Dallas, Texas

Certain dithiocarbamates were found to possess antibacterial activity. Certain bismuth derivatives were much more active than the parent compounds. Bismuth diethyldithiocarbamate was capable of protecting mice against an otherwise fatal infection caused by pneumococci (type 1).

Submitted on April 13, 1948






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Copyright © 1948 by the American Society for Pharmacology and Experimental Therapeutics.