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Journal of Pharmacology And Experimental Therapeutics, Vol. 93, Issue 2, 208-209, 1948
Copyright © 1948 by American Society for Pharmacology and Experimental Therapeutics

THE EFFECT OF CENTRAL NERVOUS SYSTEM DEPRESSANTS ON THE EMPTYING TIME OF THE HUMAX STOMACH

David W. Northup 1 and Edward J. Van Liere 1

1 Department of Physiology, School of Medicine, West Virginia University, Morgantown

The effect of therapeutic doses of chloral hydrate, bromural, pentobarbital sodium, and paraldehyde on the motility of the human stomach was studied. Consistently increased motility was found only with pentobarbital sodium, indicating that sedation is not the principal factor responsible for the decreased emptying time seen with certain central nervous system depressants (barbiturates).

Submitted on March 2, 1948




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Copyright © 1948 by the American Society for Pharmacology and Experimental Therapeutics.