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Journal of Pharmacology And Experimental Therapeutics, Vol. 92, Issue 3, 323-329, 1948
Copyright © 1948 by American Society for Pharmacology and Experimental Therapeutics

STUDIES WITH TETRAZOLE DERIVATIVES

IV. Some Pharmacologic Properties Of Aminomethyl Tetrazoles

E. G. GROSS 1 and R. M. FEATHERSTONE 1

1 Department of Pharmacology, College of Medicine, State University of Iowa

The effect on the central nervous system of 38 derivatives of aminomethyl tetrazole has been studied. This group of compounds falls into 3 distinct classes with regard to pharmacologic action, namely: convulsant, sedative, and those containing a mixture of both properties. A correlation of structure with phaemacologic activity has been attempted.

Submitted on November 19, 1947






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Copyright © 1948 by the American Society for Pharmacology and Experimental Therapeutics.