JPET xPharm- The Comprehensive Pharmacology Reference

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by MARSH, D. F.
Right arrow Articles by ROSS, C. A.
Right arrow Search for Related Content
PubMed
Right arrow Articles by MARSH, D. F.
Right arrow Articles by ROSS, C. A.
Journal of Pharmacology And Experimental Therapeutics, Vol. 92, Issue 2, 108-120, 1948
Copyright © 1948 by American Society for Pharmacology and Experimental Therapeutics

THE COMPARATIVE PHARMACOLOGY OF THE N-ALKYLARTERENOLS

DAVID F. MARSH 1, M. H. PELLETIER 1, and C. A. ROSS 1

1 Department of Pharmacology, West Virginia University School of Medicine, Morgantown, W. Va.

The effects of dl-(3 ,4-dihydroxyphenyl)-2-aminoethanol (Arterenol) and its nitrogen alkyl homologs, methyl (dl-epinephrine), ethyl, isopropyl, n-propyl, sec-butyl, and ter-butylarterenol, have been determined with the usual pharmacological test objects, including man.

These agents have both excitatory and inhibitory actions, with arterenol and dl-epinephrine having the greatest excitatory activity, the ethyl some, and the others little; while the isopropyl, ter-butyl, and ethyl have the greatest inhibitory activity, the methyl some, and the others little, with arterenol very little or none.

Submitted on May 19, 1947




This article has been cited by other articles:


Home page
 ScienceHome page
E. Beccari, A. Beretta, and J. S. Lawendel
Resolution of Isopropyl Nor-Adrenaline into Optical Isomers and Their Pharmacological Potency Ratio
Science, August 28, 1953; 118(3061): 249 - 250.
[PDF]


Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1948 by the American Society for Pharmacology and Experimental Therapeutics.