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Journal of Pharmacology And Experimental Therapeutics, Vol. 91, Issue 4, 324-330, 1947
Copyright © 1947 by American Society for Pharmacology and Experimental Therapeutics

THE COMPARATIVE PHARMACOLOGICAL ACTIVITY OF BETA-CYCLOPENTYLETHYLAMINE AND BETA-CYCLOPENTYLISOPROPYLAMINE

DAVID F. MARSH 1, M. H. PELLETIER 1, and C. A. ROSS 1

1 From the Department of Pharmacology, West Virginia University School of Medicine, Morgantown

The pharmacological activity of cyclopentylethylamine and cyclopentylisopropylamine has been compared with beta-phenylethylamine and amphetamine. The pressor activity of these compounds in barbitalized dogs, cats, and rabbits has been determined and compared with epinephrine. The action of these agents in the isolated guinea pig lung, on isolated rabbit heart, rabbit jejunum, in the intact rabbit and cat eye, on the nasal mucous membrane of man, and in man following oral administration has been determined.

Submitted on May 12, 1947






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Copyright © 1947 by the American Society for Pharmacology and Experimental Therapeutics.