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Journal of Pharmacology And Experimental Therapeutics, Vol. 91, Issue 2, 190-193, 1947
Copyright © 1947 by American Society for Pharmacology and Experimental Therapeutics

LOCAL ANESTHETIC ACTION OF A SERIES OF ARYL-URETHANES

HELEN RAMSEY 1 and H. B. HAAG 1

1 Department of Pharmacology, Medical College of Virginia, Richmond

The local anesthetic action of a series of aryl-urethane compounds has been tested. All compounds appeared to possess anesthetic activity greater than that of cocaine hydrochloride, this difference being most marked in the case of the compounds with the longer substituted alkyl groups. A correlation was shown to exist between the duration of effect and the length of the substituted alkyl group in each of the two series.

Submitted on July 18, 1947






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Copyright © 1947 by the American Society for Pharmacology and Experimental Therapeutics.