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Journal of Pharmacology And Experimental Therapeutics, Vol. 91, Issue 2, 174-177, 1947
Copyright © 1947 by American Society for Pharmacology and Experimental Therapeutics

THE DISTRIBUTION OF QUINACRINE IN DOGS AND IN RABBITS

EARL H. DEARBORN 1

1 Department of Pharmacology and Experimental Therapeutics, The Johns Hopkins University

The concentration of quinacrine in the plasma of rabbits and dogs shows marked variation. There is no significant correlation between the concentration of quinacrine in the plasma and that in the tissues of rabbits and dogs. The concentration of quinacrine in muscle and its ratio to the concentration in the plasma tend to increase in dogs on a constant daily dosage.

Submitted on July 14, 1947






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Copyright © 1947 by the American Society for Pharmacology and Experimental Therapeutics.