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Journal of Pharmacology And Experimental Therapeutics, Vol. 90, Issue 3, 211-214, 1947
Copyright © 1947 by American Society for Pharmacology and Experimental Therapeutics

A COMPARISON OF CERTAIN DIGITALIS GLYCOSIDES

A. M. WEDD 1 and H. A. BLAIR 1

1 Department of Physiology, University of Rochester School of Medicine & Dentistry, Rochester, New York

The most constant action of digitalis glycosides is to shorten the local Q-T interval. A comparison of digitoxin, ouabain, digoxin and lanatoside C using as a criterion their ability to shorten the Q-T interval of the electrogram indicated that these glycosides were qualitatively and quantitatively similar, and that the magnitude of the effect was proportional to the concentration of the drug.

Submitted on April 15, 1947






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Copyright © 1947 by the American Society for Pharmacology and Experimental Therapeutics.