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Journal of Pharmacology And Experimental Therapeutics, Vol. 89, Issue 2, 149-152, 1947
Copyright © 1947 by American Society for Pharmacology and Experimental Therapeutics


A METHOD OF SCREENING SYMPATHOMIMETIC AMINES FOR STIMULANT ACTION ON THE CEREBRUM

NANCY V. CLYMER 1 and JOSEPH SEIFTER 2

1 Wyeth Institute of Applied Biochemistry, Philadelphia, Pennsylvania
2 Wyeth Institute of A pplied Biochemistry, Philadelphia, Pennsylvania

Chicks are highly selective animals for screening compounds suspected of having a stimulant action similar to that of amphetamine because of a syndrome with a unique twittering reaction.

We wish to thank Dr. Louis S. Goodman of the University of Utah School of Medicine for the generous supply of Beta-dibenzylaminoethylchloride used in these experiments.

Submitted on November 12, 1946




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Science, December 27, 1968; 162(3861): 1442 - 1453.
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Copyright © 1947 by the American Society for Pharmacology and Experimental Therapeutics.