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Journal of Pharmacology And Experimental Therapeutics, Vol. 89, Issue 2, 106-108, 1947
Copyright © 1947 by American Society for Pharmacology and Experimental Therapeutics

THE EFFECT OF AMPHETAMINE SULFATE ON PERFORMANCE OF NORMAL AND FATIGUED SUBJECTS

HENRY W. NEWMAN M.D.1

1 Department of Medicine, Stanford University School of Medicine, San Francisco, Calif.

Amphetamine sulfate in a dose of 10 mgm. by mouth is incapable of significantly improving performance of a monotonous skilled task for a relatively short time unless this performance has been reduced by previously existing fatigue. In fatigued subjects significant restoration of performance, although not to pre-fatigue levels, usually results from this medication. Thus amphetamine sulfate may be a useful drug when necessity requires the performance of such tasks by fatigued individuals.

Submitted on August 27, 1946




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Copyright © 1947 by the American Society for Pharmacology and Experimental Therapeutics.