JPET Introducing ALZET?ew Model 2006 Pump

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Journal of Pharmacology And Experimental Therapeutics, Vol. 88, Issue 1, 10-13, 1946
Copyright © 1946 by American Society for Pharmacology and Experimental Therapeutics

COMPARISON OF PRESSOR ACTION OF ALIPHATIC AMINES

E. E. SWANSON 1 and K. K. CHEN 1

1 From the Lilly Research Laboratories, Eli Lilly and Company, Indianapolis 6, Indiana

The pressor activity of thirty-nine aliphatic amines has been compared in pithed dogs. The most active compounds are 2-amino-4-methyl-hexane and 2-amino-heptane. Presentation of results has been made in relation to chemical structure. The amino groups on C2 appears to have the most favorable influence on the pressor activity.

Submitted on May 3, 1946






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Copyright © 1946 by the American Society for Pharmacology and Experimental Therapeutics.