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Journal of Pharmacology And Experimental Therapeutics, Vol. 85, Issue 4, 343-345, 1945
Copyright © 1945 by American Society for Pharmacology and Experimental Therapeutics

THE CHOLERETIC ACTION OF DEHYDROCHOLIC ACID (DECHOLIN) AND DEOXYCHOLIC ACID (DEGALOL) IN CHRONIC BILIARY FISTULA DOGS

ELDON M. BOYD 1, W. F. PERRY 1, and W. C. STEWART 1

1 From the Department of Pharmacology, Queen's University, Kingston, Canada

Decholin and Degalol were given per ora in a dose of 0.1 gm. per kilo body weight to 16 unanesthetized, chronic biliary fistula dogs. Over a period of three days, both drugs produced an increased volume output of hepatic bile but no significant change in its specific gravity, relative viscosity, total solids, sodium, potassium, chlorides, inorganic phosphate, total fatty acids, total cholesterol, ester cholesterol, free cholesterol, bilirubin or bile acid contents.

Submitted on September 11, 1945






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Copyright © 1945 by the American Society for Pharmacology and Experimental Therapeutics.