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Journal of Pharmacology And Experimental Therapeutics, Vol. 84, Issue 1, 74-77, 1945
Copyright © 1945 by American Society for Pharmacology and Experimental Therapeutics

SUSCEPTIBILITY OF BIRDS TO INSULIN AS COMPARED WITH MAMMALS

K. K. CHEN 1, ROBERT C. ANDERSON 1, and NILA MAZE 1

1 From the Lilly Research Laboratories, Eli Lilly and Company, Indianapolis 6

By intravenous injection of insulin, the canary, pigeon, duck, and rooster are shown to be more resistant than the mouse, rat, rabbit, and dog, as judged by the convulsive dose, speed of reaction, and blood sugar determinations in the duck and rooster. Among the birds, the duck is the most, and the rooster, the least sensitive. The latter fails to develop convulsions even with lethal doses of insulin.

Submitted on March 7, 1945




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H. B. CHASE, M. S. GUNTHER, J. MILLER, and D. WOLFFSON
High Insulin Tolerance in an Inbred Strain of Mice
Science, March 19, 1948; 107(2777): 297 - 299.
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Copyright © 1945 by the American Society for Pharmacology and Experimental Therapeutics.