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Journal of Pharmacology And Experimental Therapeutics, Vol. 84, Issue 1, 12-15, 1945
Copyright © 1945 by American Society for Pharmacology and Experimental Therapeutics

A METHOD FOR THE DETERMINATION OF ANALEPTIC ACTIVITY

L. G. GOODWIN 1 and P. B. MARSHALL 1

1 From the Wellcome Laboratories of Tropical Medicine, 183 Euston Road, London, England

1. A modification of Chakravarti's analeptic test is described, in which adequate controls are used in each experiment.

2. The effects of several widely-used stimulants upon mice anaesthetised with nembutal have been compared. The results have been assessed by an application of the "time-response curve" method.

Submitted on December 22, 1944




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