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Journal of Pharmacology And Experimental Therapeutics, Vol. 82, Issue 3, 288-291, 1944
Copyright © 1944 by American Society for Pharmacology and Experimental Therapeutics

ANESTHESIA

XVI. THE DETERMINATION OF ISOPROPENYL VINYL OXIDE IN THE BLOOD OF ANESTHETIZED ANIMALS

WILLIAM E. EVANS JR. 1, C. JELLEFF CARR 1, VIRGINIA M. WATERS 1, and JOHN C. KRANTZ JR. 1

1 Department of Pharmacology, School of Medicine, University of Maryland, Baltimore, Md.

1. A method has been devised to determine propethylene in blood.

2. The anesthetic concentrations of propethylene in dog's blood lie between 30 and 40 mg. per cent. It is somewhat less in the monkey.

3. Propethylene for the most part is stable in the blood of the dog and monkey. Approximately 2.5 per cent of the blood concentration undergoes hydrolysis within a period of 3 hours.

Submitted on September 18, 1944






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Copyright © 1944 by the American Society for Pharmacology and Experimental Therapeutics.