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Journal of Pharmacology And Experimental Therapeutics, Vol. 82, Issue 1, 86-88, 1944
Copyright © 1944 by American Society for Pharmacology and Experimental Therapeutics

THE EFFECT OF ASCORBIC ACID ON THE ACUTE TOXICITY OF SULFANILAMIDE FOR GUINEA PIGS

LEONARD KAREL 1 and C. W. CHAPMAN 1

1 Department of Pharmacology, University of Maryland School of Pharmacy

1. The LD50 of sulfanilamide for fasting guinea pigs is significantly less than that for non-fasting animals.

2. Vitamin C has no influence on the acute toxicity of sulfanilamide for guinea pigs.

Submitted on June 28, 1941






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Copyright © 1944 by the American Society for Pharmacology and Experimental Therapeutics.