JPET

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by ANDREWS, H. L.
Right arrow Articles by HIMMELSBACH, C. K.
Right arrow Search for Related Content
PubMed
Right arrow Articles by ANDREWS, H. L.
Right arrow Articles by HIMMELSBACH, C. K.
Journal of Pharmacology And Experimental Therapeutics, Vol. 81, Issue 3, 288-293, 1944
Copyright © 1944 by American Society for Pharmacology and Experimental Therapeutics

RELATION OF THE INTENSITY OF THE MORPHINE ABSTINENCE SYNDROME TO DOSAGE

HOWARD L. ANDREWS 1 and C. K. HIMMELSBACH 1

1 The Research Division, The U. S. Public Health Service Hospital, Lexington, Kentucky

Data on the abstinence syndrome intensities of 127 morphine addicts stabilized on doses ranging from 40 to 500 mg. per day indicate that a functional relationship exists between the total abstinence syndrome for seven days (T.A.S.-7) and the stabilization dose. From the form of this function it appears that a maximum T.A.S.-7 would be expected at a daily dose of about 500 mg. The theoretical implications and a practical application are discussed.

Submitted on May 18, 1944




This article has been cited by other articles:


Home page
 Palliat MedHome page
N. Sykes
An investigation of the ability of oral naloxone to correct opioid-related constipation in patients with advanced cancer
Palliative Medicine, April 1, 1996; 10(2): 135 - 144.
[Abstract] [PDF]

Home page
 Arch Intern MedHome page
L. LASAGNA
NALORPHINE (N-ALLYLNORMORPHINE) Practical and Theoretical Considerations
Arch Intern Med, October 1, 1954; 94(4): 532 - 558.
[Abstract] [PDF]


Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1944 by the American Society for Pharmacology and Experimental Therapeutics.