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1 From the Research Service, Third (New York University) Medical Division, Goldwater Memorial Hospital, Welfare Island, New York, and the Department of Medicine, New York University College of Medicine, New York
A method is described for the estimation of salicylic acid in plasma. The salicylic acid is separated from plasma by extraction with ethylene dichloride from an acid medium. It is then returned as the colored iron complex to an aqueous phase and determined colorimetrically. The procedure is simple and permits the routine estimation of the plasma concentrations of salicylic acid achieved with the usual therapeutic doses.
Submitted on November 19, 1943
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