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Journal of Pharmacology And Experimental Therapeutics, Vol. 79, Issue 3, 235-239, 1943
Copyright © 1943 by American Society for Pharmacology and Experimental Therapeutics

EXPERIMENTS ON THE PHARMACOLOGY OF RESPIRATION IN THE RABBIT

V. E. HENDERSON 1 and C. L. YI 1

1 Department of Pharmacology, University of Toronto

1. Evidence is presented in this paper that the stimulant drugs, cocaine, nikethamide, metrazol, nicotine, cyanide, picrotoxin, strychnine and caffeine, in appropriate doses, produce an increase in respiratory rate by acting on the respiratory cells.

2. That the depressant drugs, morphine and barbitone, decrease respiratory rate by acting again on the respiratory cells.

Submitted on July 26, 1943






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Copyright © 1943 by the American Society for Pharmacology and Experimental Therapeutics.