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Journal of Pharmacology And Experimental Therapeutics, Vol. 79, Issue 2, 133-135, 1943
Copyright © 1943 by American Society for Pharmacology and Experimental Therapeutics


THE ACTION OF CARTHAMOIDINE

PAUL N. HARRIS 1, ROBERT C. ANDERSON 1, and K. K. CHEN 1

1 From the Lilly Research Laboratories, Eli Lilly and Company, Indianapolis

Carthamoidine in suitable doses produces slow death and necrosis of the liver in mice when injected intravenously. The lesion is predominantly periportal, similar to that caused by pterophine. Carthamoidine inhibits the isolated rabbit's intestines, stimulates the isolated guinea pig's uterus, and lowers blood pressure in etherized cats.

Submitted on June 30, 1943







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Copyright © 1943 by the American Society for Pharmacology and Experimental Therapeutics.