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1 From the Lilly Research Laboratories, Eli Lilly and Company, Indianapolis
Carthamoidine in suitable doses produces slow death and necrosis of the liver in mice when injected intravenously. The lesion is predominantly periportal, similar to that caused by pterophine. Carthamoidine inhibits the isolated rabbit's intestines, stimulates the isolated guinea pig's uterus, and lowers blood pressure in etherized cats.
Submitted on June 30, 1943