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Journal of Pharmacology And Experimental Therapeutics, Vol. 79, Issue 1, 23-26, 1943
Copyright © 1943 by American Society for Pharmacology and Experimental Therapeutics


THE REDUCTION OF SYMMETRICAL TRINITROTOLUENE BY A SUCCINIC DEHYDROGENASE PREPARATION

BENTON B. WESTFALL 1

1 From the Division of Chemotherapy, National Institute of Health, U. S. Public Health Service

1. A succinic dehydrogenase preparation has been examined for its reducing action on symmetrical trinitrotoluene.

The preparation rapidly reduces the toluene derivative to a product which behaves on diazotization like the 4 amino compound.

2. The reduction is influenced by various agents to a similar extent and in much the same manner as has been established by others for the influence of these agents on the activity of this preparation as a dehydrogenase.

Submitted on May 13, 1943







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Copyright © 1943 by the American Society for Pharmacology and Experimental Therapeutics.