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Journal of Pharmacology And Experimental Therapeutics, Vol. 78, Issue 1, 90-92, 1943
Copyright © 1943 by American Society for Pharmacology and Experimental Therapeutics


THE EFFECT OF HIGH FAT DIET ON CHRONIC TOXICITY OF DERRIS AND ROTENONE

ANTHONY M. AMBROSE 1, FLOYD DEEDS 1, and ALVIN J. COX JR. 1

1 From the Bureau of Agricultural Chemistry and Engineering, Agricultural Research Administration, U. S. Department of Agriculture at the Department of Pharmacology, and the Department of Pathology, Stanford University School of Medicine, San Francisco, California

Albino rats have been maintained on high fat diets containing derris and rotenone for a minimum of 140 days. Growth curves failed to show any appreciable retardation of growth of the experimental rats as compared with control rats. Histological examination of the tissues failed to show any evidence of tissue damage.

Submitted on February 9, 1943







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Copyright © 1943 by the American Society for Pharmacology and Experimental Therapeutics.