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Journal of Pharmacology And Experimental Therapeutics, Vol. 77, Issue 4, 311-316, 1943
Copyright © 1943 by American Society for Pharmacology and Experimental Therapeutics

A SPLENIC CONTRACTING SUBSTANCE IN ORANGE SEEDS

FRANCISCO T. MACIAS 1, RALPH G. SMITH 1, and FOSTER N. MARTIN JR. 1

1 From the Department of Pharmacology, University of Michigan Medical School, Ann Arbor

A crude extract of orange seeds contains a water soluble substance of comparatively low toxicity which produces strong splenic contraction. Although an active principle has not been isolated definite progress has been made in its purification.

Submitted on August 31, 1942






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Copyright © 1943 by the American Society for Pharmacology and Experimental Therapeutics.