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Journal of Pharmacology And Experimental Therapeutics, Vol. 76, Issue 2, 167-174, 1942
Copyright © 1942 by American Society for Pharmacology and Experimental Therapeutics

CERBERIN AND CERBEROSIDE, THE CARDIAC PRINCIPLES OF CERBERA ODOLLAM

K. K. CHEN 1 and FRANK A. STELDT 1

1 From the Lilly Research Laboratories, Indianapolis, Indiana

1. Cerberin can be isolated from both the oil and the defatted kernels of Cerbera odollam nuts.

2. From a second batch of nuts, a glycoside similar to but not identical with cerberin has been isolated, to which the name of cerberoside has been proposed.

3. Both cerberin and cerberoside have a digitalis-like action. Cerberin is much more potent on the heart than cerberoside.

Submitted on June 22, 1942






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Copyright © 1942 by the American Society for Pharmacology and Experimental Therapeutics.