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Journal of Pharmacology And Experimental Therapeutics, Vol. 76, Issue 1, 11-16, 1942
Copyright © 1942 by American Society for Pharmacology and Experimental Therapeutics

DRUG PROPHYLAXIS AGAINST LETHAL EFFECTS OF SEVERE ANOXIA III. d-, l- AND dl-PHENISOPROPYLAMINES

G. A. EMERSON 1

1 From the Department of Pharmacology, West Virginia University School of Medicine, Morgantown

dl-Phenisopropylamine (benzedrine) and its optically active isomers have no prophylactic value against lethal actions of acute anoxia in mice, when administered in doses comparable to those used therapeutically in man, and are significantly detrimental to anoxic mice when administered in higher sublethal amounts.

Submitted on April 27, 1942






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Copyright © 1942 by the American Society for Pharmacology and Experimental Therapeutics.