JPET Introducing ALZET?ew Model 2006 Pump

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by ROBERTS, R. G.
Right arrow Articles by JACKMAN, A. WM.
Right arrow Search for Related Content
PubMed
Right arrow Articles by ROBERTS, R. G.
Right arrow Articles by JACKMAN, A. WM.
Journal of Pharmacology And Experimental Therapeutics, Vol. 74, Issue 4, 392-394, 1942
Copyright © 1942 by American Society for Pharmacology and Experimental Therapeutics

THE ACTIVITY OF DERIVATIVES OF CURARE AS PREPARED IN LIQUID AMMONIA

RICHARD G. ROBERTS 1, ROY A. HECHT 1, and A. WM. JACKMAN 1

1 From the Department of Physiological Chemistry of The Chicago Medical School, Chicago, Illinois

1. Liquid ammonia does not inactivate curare by remaining in contact with it for 48 hours.

2. Curare which has been treated with liquid ammonia forms a much finer dispersion in water than does untreated curare.

3. Curare can be fractionated in liquid ammonia by the use of sintered glass filters with the removal of more than 50% of inert material.

4. The insoluble fraction of curare in liquid ammonia when treated with glycine becomes more potent, prolonged in action and less toxic than curare.

Submitted on December 29, 1941






Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1942 by the American Society for Pharmacology and Experimental Therapeutics.