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Journal of Pharmacology And Experimental Therapeutics, Vol. 73, Issue 4, 441-445, 1941
Copyright © 1941 by American Society for Pharmacology and Experimental Therapeutics


THE EFFECT OF CERTAIN ANESTHETICS ON BLOOD KETO ACID LEVELS

WM. M. GOVIER 1 and C. M. GREER 1

1 From the Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee

1. A rise in blood keto acid levels may occur in dogs anesthetized with diethyl ether and in those anesthetized with cyclopropane.

2. Elevated keto acid values occurring in dogs under ether anesthesia may be reduced by administration of thiamin.

3. Pentothal-sodium, pentobarbital sodium, and 5,5-Di-n-propyl-2,4-oxazolidinedione produce no elevation in blood keto acid values.

Submitted on August 14, 1941







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Copyright © 1941 by the American Society for Pharmacology and Experimental Therapeutics.