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Journal of Pharmacology And Experimental Therapeutics, Vol. 73, Issue 2, 170-172, 1941
Copyright © 1941 by American Society for Pharmacology and Experimental Therapeutics

STUDIES ON THE ACUTE TOXICITY OF SULFACETIMIDE (PARA-AMINOBENZENE SULFONYL ACETYL IMIDE)

RICHARD DONOVICK 1 and EDWARD HENDERSON 1

1 From the Department of Urology, College of Physicians and Surgeons, Columbia University, New York and the Medical Research Division, Schering Corporation, Bloomfield, New Jersey

Mice tolerate single doses as high as 7.5 grams of sodium sulfacetimide per kilogram body weight when administered subcutaneously. The LD50 of this compound lies between 9.7 and 10.0 grams per kilogram.

Submitted on July 7, 1941






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Copyright © 1941 by the American Society for Pharmacology and Experimental Therapeutics.