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1 From the Department of Pharmacology, School of Medicine, University of Mississippi, University
Blood coagulation time was determined in dogs anesthetized with sodium pentobarbital. Several drugs, previously reported to have systemic clotting effects, were found to be without distinct influence on blood coagulation time under these conditions. The same experimental conditions proved to be uniformly responsive to small, stepwise graded doses of anti-coagulant drugs.
Submitted on June 25, 1941