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Journal of Pharmacology And Experimental Therapeutics, Vol. 71, Issue 4, 320-324, 1941
Copyright © 1941 by American Society for Pharmacology and Experimental Therapeutics

CYVERINE HYDROCHLORIDE, A NEW SYNTHETIC PAPAVERINE-LIKE COMPOUND A REPORT ON ITS VASODILATOR ACTION IN CHRONIC OCCLUSIVE PERIPHERAL VASCULAR DISEASES

ROY J. POPKIN 1

1 From the Department of Peripheral Vascular Diseases, Outpatient Clinic, Cedars of Lebanon Hospital, Los Angeles, California

1. Cyverine hydrochloride administered orally frequently causes unpleasant symptoms as heartburn, headaches and dizziness.

2. Its vasodilator action, as shown by surface temperatures, oscillometer readings and clinical improvement, is negligible.

3. It is not recommended as a vasodilator in chronic obliterative peripheral vascular diseases.

Submitted on November 1, 1940




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 Arch Intern MedHome page
G. W. SCUPHAM, G. DE TAKATS, T. R. VAN DELLEN, and J. H. JESSER
VASCULAR DISEASES: SEVENTH ANNUAL REVIEW
Arch Intern Med, September 1, 1941; 68(3): 599 - 660.
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Copyright © 1941 by the American Society for Pharmacology and Experimental Therapeutics.