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Journal of Pharmacology And Experimental Therapeutics, Vol. 69, Issue 2, 166-170, 1940
Copyright © 1940 by American Society for Pharmacology and Experimental Therapeutics

THE COMPARATIVE THERAPEUTIC ACTIVITY OF SULFANILAMIDE, SULFAPYRIDINE, SULFATHIAZOLE AND DIAMINOSULPHONE IN TYPE I PNEUMOCOCCUS INFECTIONS IN MICE

J. T. LITCHFIELD JR. 1, H. J. WHITE 1, and E. K. MARSHALL JR. 1

1 From the Department of Pharmacology and Experimental Therapeutics, The Johns Hopkins University

A comparison of the therapeutic activity of sulfanilamide, sulfathiazole, and diaminosulfone with the activity of sulfapyridine against a pneumococcus infection in mice gave, on the basis of Median Survival Blood Concentrations, activity ratios of 0.43, 1.21 and 6.86 respectively.

Submitted on April 20, 1940






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