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Journal of Pharmacology And Experimental Therapeutics, Vol. 69, Issue 1, 37-39, 1940
Copyright © 1940 by American Society for Pharmacology and Experimental Therapeutics

FURTHER RESULTS WITH VARIOUS AGENTS IN EXPERIMENTAL HYPERTHYROIDISM

WINDSOR C. CUTTING 1 and WILLIAM C. KUZELL 1

1 From the Department of Pharmacology, Stanford University School of Medicine, San Francisco, Calif.

Sulfanilamide and phenobarbital were found to reduce the degree of experimental hyperthyroidism produced by thyrotropic hormone or thyroxin in guinea pigs, by a general depressant action. Chloral acted similarly, but was quite toxic. Testosterone, testosterone plus colchicine, and calcium gluconate, in tolerable doses, did not demonstrably affect the degree of hyperthyroidism from thyrotropic hormone.

Submitted on February 5, 1940






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