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Journal of Pharmacology And Experimental Therapeutics, Vol. 68, Issue 2, 247-251, 1940
Copyright © 1940 by American Society for Pharmacology and Experimental Therapeutics

THE INFLUENCE OF EPINEPHRINE ON SHIVERING AND ON METABOLISM IN THE COLD

V. E. HALL 1 and P. B. GOLDSTONE 1

1 From the Department of Physiology, Stanford University, California

In cooled pentobarbitalized cats, epinephrine, in doses just in excess of the physiological rate of secretion, suppresses shivering and consequently reduces the total metabolism by decreasing the amount of oxygen consumed by this activity. These effects are attributed to a depression by epinephrine of the central motor mechanisms involved in the execution of shivering.

Submitted on September 19, 1939






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Copyright © 1940 by the American Society for Pharmacology and Experimental Therapeutics.