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Journal of Pharmacology And Experimental Therapeutics, Vol. 67, Issue 4, 407-422, 1939
Copyright © 1939 by American Society for Pharmacology and Experimental Therapeutics


THE INTEGRATION OF THE VASOMOTOR RESPONSES IN THE LIVER WITH THOSE IN OTHER SYSTEMIC VESSELS

L. N. KATZ 1 and S. RODBARD 1

1 From the Cardiovascular Dept., Michael Reese Hospital, Chicago, Illinois

1. The dynamic interrelationships between the blood flow in the thoracic inferior vena cava and the portal vein and the arterial, venous and portal pressures were studied in the intact anesthetized dog.

2. The effects of adrenalin, histamine, pitressin, amyl nitrite, acetylcholine, mecholyl, atropine, saline and vagus section on the hepatoportal and systemic circuits are analyzed.

3. It is shown that the factors involved are integrated in different ways by different drugs, depending on the location of the dominating mechanism brought into action by the drug.

Submitted on June 15, 1939




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Copyright © 1939 by the American Society for Pharmacology and Experimental Therapeutics.