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Journal of Pharmacology And Experimental Therapeutics, Vol. 66, Issue 3, 336-349, 1939
Copyright © 1939 by American Society for Pharmacology and Experimental Therapeutics

THE ACTION OF CERTAIN DRUGS ON RESPIRATORY REFLEXES

V. E. HENDERSON 1 and H. V. RICE 1

1 Department of Pharmacology, University of Toronto, Ontario, Canada

The effects of three drugs, morphine, ether and coramine upon some reflexes affecting respiration, have been investigated. It was shown that the action of the drugs in many ways resembles the effects produced by increased or decreased concentrations of CO2 in the inspired air. Such results support the opinion held by many that the respiratory effects of these drugs is the result of a change in the receptivity of the cells of the respiratory centre toward CO2.

Submitted on January 18, 1939






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Copyright © 1939 by the American Society for Pharmacology and Experimental Therapeutics.