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Journal of Pharmacology And Experimental Therapeutics, Vol. 65, Issue 4, 383-388, 1939
Copyright © 1939 by American Society for Pharmacology and Experimental Therapeutics

INFLUENCE OF AGE AND WEIGHT OF PIGS ON RESPONSE TO SODIUM EVIPAN

H. P. DONALD 1 and J. RAVENTÓS 1

1 From the Institute of Animal Genetics and the Department of Pharmacology, University of Edinburgh

1. New-born pigs (2 to 4 days old; 1 to 2 kgm.) are more susceptible to sodium evipan than older pigs (2 to 30 kgm.).

2. A constant narcotic response is produced by 20 mgm. per kilogram sodium evipan in young pigs between the ages of about 10 days (weight 2.6 kgm.) and 80 days (weight 20 kgm.), whilst 6 months old pigs (64 kgm.) are somewhat more susceptible.

3. One litter showed a consistently shorter duration of narcosis than did the remainder, during the first month of life.

Submitted on July 14, 1938






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Copyright © 1939 by the American Society for Pharmacology and Experimental Therapeutics.