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Journal of Pharmacology And Experimental Therapeutics, Vol. 65, Issue 4, 343-352, 1939
Copyright © 1939 by American Society for Pharmacology and Experimental Therapeutics


ADDITIONAL DATA CONCERNING THE CHEMISTRY OF THE PRESSOR AND OXYTOCIC HORMONES OF THE PITUITARY GLAND

R. L. STEHLE 1 and S. M. TRISTER 1

1 Department of Pharmacology, McGill University, Montreal

From the pressor hormone of the posterior lobe of the pituitary gland arginine has been isolated as the flavianate and proline as the reineckate. A hydantoin indicating the presence of isoleucine and another indicating the presence of cystine was isolated. Cystine and tyrosine crystals were also seen. Histidine, hydroxyproline and glycine were shown to be absent and tryptophane is present only in traces if present at all.

The oxytocic hormone appears to contain leucine instead of isoleucine; otherwise the constituent amino acids are the same as those of the pressor hormone.

Submitted on May 31, 1938




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Arch Intern MedHome page
E. H. RYNEARSON and L. R. SCHWEIGER
REVIEW OF LITERATURE ON THE PITUITARY BODY (1938 AND 1939)
Arch Intern Med, July 1, 1940; 66(1): 226 - 290.
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Copyright © 1939 by the American Society for Pharmacology and Experimental Therapeutics.