JPET

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by ROBBINS, B. H.
Right arrow Articles by FITZHUGH, O. G.
Right arrow Search for Related Content
PubMed
Right arrow Articles by ROBBINS, B. H.
Right arrow Articles by FITZHUGH, O. G.
Journal of Pharmacology And Experimental Therapeutics, Vol. 65, Issue 2, 136-142, 1939
Copyright © 1939 by American Society for Pharmacology and Experimental Therapeutics

STUDIES OF CYCLOPROPANE V. THE EFFECT OF MORPHINE, BARBITAL, AND AMYTAL UPON THE CONCENTRATION OF CYCLOPROPANE IN THE BLOOD REQUIRED FOR ANESTHESIA AND RESPIRATORY ARREST

BENJAMIN H. ROBBINS 1, J. H. BAXTER JR. 1, and O. GARTH FITZHUGH 1

1 From the Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee

The effect of premedication with morphine, barbital, or amytal upon the concentration of cyclopropane in the blood necessary for the different levels of anesthesia and respiratory arrest has been determined on 28 dogs.

With the smaller doses of the drugs used there was a marked reduction in the amount of cyclopropane necessary for surgical anesthesia without an appreciable reduction in the concentration necessary to produce respiratory arrest.

With the larger doses of the drugs used, partial summation was present in all stages and at respiratory arrest.

Submitted on June 15, 1938




This article has been cited by other articles:


Home page
 Arch SurgHome page
B. H. ROBBINS
PREANESTHETIC MEDICATION
Arch Surg, June 1, 1940; 40(6): 1044 - 1056.
[Abstract] [PDF]


Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1939 by the American Society for Pharmacology and Experimental Therapeutics.