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Journal of Pharmacology And Experimental Therapeutics, Vol. 65, Issue 1, 79-88, 1939
Copyright © 1939 by American Society for Pharmacology and Experimental Therapeutics

THE EFFECT OF THE DIET UPON THE ANESTHETIC QUALITIES OF SOME HYPNOTICS

AXEL M. HJORT 1, EDWIN J. DEBEER 1, and DAVID W. FASSETT 1

1 From The Burroughs Wellcome & Co. U. S. A. Experimental Research Laboratories, Tuckahoe, New York

1. Significant differences in the minimum hypnotic (H 50) and minimum lethal (L 50) doses of unsymmetrical n-propyl-o-tolylurea were found in groups of mice fed two widely different diets.

2. There is a remarkable difference in the duration of anesthesia following the administration of several hypnotics to mice fed a variety of diets.

Submitted on May 19, 1938






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Copyright © 1939 by the American Society for Pharmacology and Experimental Therapeutics.