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Journal of Pharmacology And Experimental Therapeutics, Vol. 64, Issue 3, 319-329, 1938
Copyright © 1938 by American Society for Pharmacology and Experimental Therapeutics

THE INACTIVATION AND ELIMINATION OF PICROTOXIN

JAMES M. DILLE 1

1 From the Department of Pharmacology, College of Pharmacy, University of Washington, Seattle, Washington

Picrotoxin is rapidly detoxified after intravenous administration to rabbits.

Traces of a convulsion-producing substance assumed to be picrotoxin can be detected in the urine of rabbits 18 hours after they have been given an intravenous convulsive dose.

Submitted on April 20, 1938






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Copyright © 1938 by the American Society for Pharmacology and Experimental Therapeutics.