JPET

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by MORRELL, C. A.
Right arrow Articles by ALLMARK, M. G.
Right arrow Search for Related Content
PubMed
Right arrow Articles by MORRELL, C. A.
Right arrow Articles by ALLMARK, M. G.
Journal of Pharmacology And Experimental Therapeutics, Vol. 64, Issue 1, 14-42, 1938
Copyright © 1938 by American Society for Pharmacology and Experimental Therapeutics

ON THE THERAPEUTIC ASSAY OF NEOARSPHENAMINE WITH TRYPANOSOMA EQUIPERDUM

C. A. MORRELL 1, C. W. CHAPMAN 1, and M. G. ALLMARK 1

1 From the Laboratory of Hygiene, Department of Pensions and National Health, Ottawa, Canada

1. A method for testing the therapeutic potency of neoarsphenamine preparations in terms of a standard by means of dosage-response curves is described.

2. White rats infected with T. equiperdum were used as test material.

3. There is less time and labor involved in the method described than in other methods currently in use for this purpose, since results are obtained five hours after injecting neoarsphenamine, and it is unnecessary to count the number of trypanosomes in each rat before use.

4. The results obtained by the method in the assay of some market samples are reported.

5. The errors of the method have been computed and are shown to be small.

6. A discussion is given of various methods of arranging the test and calculating the results and their errors.

Submitted on January 27, 1938






Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1938 by the American Society for Pharmacology and Experimental Therapeutics.