![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
![[Contents]](/icons/banner/tocACT.gif){kind=icon}
|
|
|
|
|
||
1 Monson State Hospital, Palmer, Massachusetts
The effects of prostigmin in 9 patients with epilepsy is reported. With a 1 mgm. dose one of 6 patients exhibited the effects of moderate peristalsis and sweating in the axillae, occurring half hour after medication and disappearing in half hour. Three patients received 2 mgm. of prostigmin. One showed no demonstrable reaction. One patient developed muscular fibrillation, and increased peristalsis twenty-five minutes after prostigmin. These effects persisted for two hours and twenty-five minutes and were abolished at that time by atropine sulfate.
The last patient developed increased peristalsis in half hour after prostigmin, which was accompanied by projectile vomiting and faintness one hour and twenty minutes after prostigmin.
None of the patients exhibited any miosis or cardiovascular changes from prostigmin.
The reactions did not differ from the manner in which normal men react to prostigmin (9).
Submitted on July 19, 1937
 |
 |
 |
|
 |
 |
 |
