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Journal of Pharmacology And Experimental Therapeutics, Vol. 61, Issue 1, 103-106, 1937
Copyright © 1937 by American Society for Pharmacology and Experimental Therapeutics

COMPARATIVE INTRAVENOUS TOXICITY OF SOME MONOHYDRIC SATURATED ALCOHOLS

A. J. LEHMAN 1 and H. W. NEWMAN 1

1 From the Department of Pharmacology and Department of Medicine, Division of Neuropsychiatry, Stanford University School of Medicine, San Francisco, California

1. The relative toxicity and anesthetic efficiency of methyl, ethyl, normal propyl, iso-butyl, and iso-amyl alcohols determined intravenously and uniformly in rabbits are reported. Some of the minimum lethal doses differed appreciably from those reported in the literature.

2. Assigning the value of 1 to ethyl alcohol, the toxic efficiency of the methyl, normal propyl, iso-butyl and iso-amyl alcohols was 0.59, 2.33, 3.56, and 5.99, respectively.

Submitted on May 21, 1937






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