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Journal of Pharmacology And Experimental Therapeutics, Vol. 60, Issue 3, 245-253, 1937
Copyright © 1937 by American Society for Pharmacology and Experimental Therapeutics

RETICULOCYTOSIS IN THE GUINEA PIG II. THE HAEMATOPOIETIC RESPONSE OF "REACTIVE" GUINEA PIGS TO ANAHAEMIN AND OTHER SUBSTANCES

M. M.O. BARRIE 1

1 From the Physiological Laboratories of The British Drug Houses Limited, London

1. "Reactive guinea pigs" give a reticulocyte response to l-histidine monohydrochloride and to hydrochloric acid.

2. The response to anahaemin is greatly in excess of that produced by any other substance tested.

3. It is suggested that histidine hydrochloride stimulates gastric secretion and hence increases the availability of the extrinsic factor.

Submitted on January 27, 1937






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Copyright © 1937 by the American Society for Pharmacology and Experimental Therapeutics.