JPET Celsis microsomes equal better data

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Journal of Pharmacology And Experimental Therapeutics, Vol. 56, Issue 4, 417-420, 1936
Copyright © 1936 by American Society for Pharmacology and Experimental Therapeutics

THE ANTAGONISM BETWEEN POSTERIOR LOBE PITUITARY HORMONES AND INSULIN

H. C. ELLSWORTH 1

1 Department of Pharmacology, McGill University, Montreal

Evidence is offered that mild insulin hypoglycemia in dogs can be completely abolished by small doses of the oxytocic hormone of the posterior lobe of the pituitary; corresponding doses of the pressor fraction have little or no effect. Larger doses of the oxytocic hormone not only abolish the insulin effect but cause a rise in the blood sugar level above normal.

Submitted on December 30, 1935






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Copyright © 1936 by the American Society for Pharmacology and Experimental Therapeutics.