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Journal of Pharmacology And Experimental Therapeutics, Vol. 56, Issue 3, 327-340, 1936
Copyright © 1936 by American Society for Pharmacology and Experimental Therapeutics

THE EFFECTS OF MORPHINE AND ITS DERIVATIVES ON INTESTINAL MOVEMENTS V. CONTRIBUTIONS TO THE ANALYSIS OF INTESTINAL RECORDS

HUGO KRUEGER 1, ISADORE LAMPE 1, and J. G. REID 1

1 From the Departments of Pharmacology and Roentgenology, University of Michigan Medical School, Ann Arbor, Michigan

Fluoroscopic visualization and X-ray films have shown that the P-waves of kymographic records of intestinal motility are caused by peristalsis. Most of the other waves on such a record are due to localized activity. The increase in tone following moderate doses of morphine usually does not involve all the musculature over a balloon to the same extent. Rhythmic contractions are not identical with segmenting contractions but are the result of activity involving the musculature over nearly the entire length of the balloon.

Submitted on December 5, 1935






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Copyright © 1936 by the American Society for Pharmacology and Experimental Therapeutics.