JPET xPharm- The Comprehensive Pharmacology Reference

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by WRIGHT, C. I.
Right arrow Articles by BARBOUR, F. A.
Right arrow Search for Related Content
PubMed
Right arrow Articles by WRIGHT, C. I.
Right arrow Articles by BARBOUR, F. A.
Journal of Pharmacology And Experimental Therapeutics, Vol. 56, Issue 1, 39-49, 1936
Copyright © 1936 by American Society for Pharmacology and Experimental Therapeutics

THE RESPIRATORY EFFECTS OF MORPHINE, CODEINE AND RELATED SUBSTANCES V. THE EFFECT OF agr, beta, ugr, DIHYDRO-agr-, DIHYDRO-beta- AND DIHYDRO-ugr-ISOMORPHINE ON THE RESPIRATION OF THE RABBIT

CHARLES I. WRIGHT 1 and FLEMING A. BARBOUR 1

1 From the Laboratory of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan

(1) agr-Isomorphine, (2) dihydro-agr-isomorphine, (3) beta-isomorphine, (4) dihydro-beta-isomorphine, (5) ugr-isomorphine, and (6) dihydro-ugr-isomorphine have been compared as to their effectiveness in decreasing the rabbit's respiratory rate, minute volume and sensitivity to carbon dioxide. The minimum subcutaneous doses (mgm. per kgm. of base) required to depress the respiratory mechanism of the rabbit are approximately (1) 0.55, (2) 0.4, (3) 8.0, (4) 0.55, (5) 8.0 and (6) 5.3.

Submitted on September 21, 1935






Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1936 by the American Society for Pharmacology and Experimental Therapeutics.