JPET Introducing ALZET?ew Model 2006 Pump

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Journal of Pharmacology And Experimental Therapeutics, Vol. 54, Issue 2, 167-187, 1935
Copyright © 1935 by American Society for Pharmacology and Experimental Therapeutics

THE PHARMACOLOGICAL ACTION OF PUKATEINE

WILLIAM S. FOGG 1

1 From the Department of Physiology, Otago University, New Zealand

1. Depression of all muscle (smooth, cardiac, and striped) with the possible exception of the uterus.

2. Depression of conductivity of nerve.

3. Depression and excitation of the central nervous system in a manner similar to morphine. The depression of the respiratory centre is the most marked.

4. Vaso-dilatation of peripheral vessels which, in conjunction with the reduced output from the heart, produces a fall in blood pressure.

5. The effect on the refractory period and the prevention of fibrillation is also described.

Submitted on July 15, 1934






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Copyright © 1935 by the American Society for Pharmacology and Experimental Therapeutics.