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Journal of Pharmacology And Experimental Therapeutics, Vol. 53, Issue 3, 347-349, 1935
Copyright © 1935 by American Society for Pharmacology and Experimental Therapeutics

THE ACTION OF DIURETICS INJECTED INTO ONE KIDNEY OF THE AGLOMERULAR TOADFISH

RAYMOND N. BIETER 1

1 From the Department of Pharmacology, The University of Minnesota Medical School, Minneapolis

Under the conditions described, the injections of MgSO4, MgCl2, CaCl2, Na2SO4, creatinine and urea solutions, in doses of 0.02 cc., into the renal portal vein system of one kidney, produces a diuresis, only on the injected side. Therefore these effects appear to be renal in origin.

When these same solutions of the salts are injected in a similar manner, in volumes up to 0.25 cc., the opposite kidney also shows a diuresis. The effect on the opposite side, however, is slower in onset and much less marked.

Submitted on December 26, 1934




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Copyright © 1935 by the American Society for Pharmacology and Experimental Therapeutics.